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Photo of Anthony and Jeanne Pritzker.

UCLA psychology department receives $30 million from Anthony & Jeanne Pritzker Family Foundation

Photo of Anthony and Jeanne Pritzker.

Anthony and Jeanne Pritzker at the Hammer gala in 2019. (Photo credit: Courtesy of the Pritzkers)

UCLA has received a $30 million commitment from the Anthony and Jeanne Pritzker Family Foundation to support a major renovation of the Psychology Tower on the UCLA campus. In recognition of the gift, the building has been named Pritzker Hall.

Tony Pritzker served as co-chair of the Centennial Campaign for UCLA, which concluded in December. The campaign exceeded its original $4.2 billion fundraising goal 18 months ahead of schedule.

“Tony’s visionary leadership and unwavering support has inspired unprecedented philanthropy to UCLA throughout the campaign, helping cement a strong foundation for our second century,” UCLA Chancellor Gene Block said. “Now, thanks to Tony and Jeanne’s latest extraordinary gift, UCLA Psychology will be primed for decades of trailblazing research and exceptional teaching.”

The $30 million commitment is the second largest in the history of the UCLA College’s life sciences division, which is home to the psychology department. Of the total amount, $10 million will create the Anthony and Jeanne Pritzker Endowment for Excellence, which will provide faculty and student support and fund ongoing infrastructure needs.

Photo of an architect’s rendering of Pritzker Hall from above.

An architect’s rendering of Pritzker Hall from above. (Photo courtesy of CO Architects)

“We have tremendous confidence in UCLA, as a public university, to move society and the world forward, which is why we invest our time and resources there,” Tony Pritzker said. “We are pleased to build upon our foundation’s earlier commitments to UCLA, while strengthening the extraordinary reputation that the psychology department’s research and scholarship have rightfully earned.”

The donation bookends the Anthony and Jeanne Pritzker Family Foundation’s Centennial Campaign giving to the UCLA College; the foundation also gave $15 million to the UCLA Institute of the Environment and Sustainability in 2013, before the campaign’s public launch. The Pritzker Foundation’s total giving to UCLA, which also includes major gifts to athletics, law, medicine, neuroscience, education, public policy and programs to support foster youth on campus, now stands at just under $100 million.

“We are immensely grateful to Tony and Jeanne Pritzker for taking the lead in investing in a new era for UCLA Psychology,” said Victoria Sork, dean of life sciences. “I am especially heartened by this gift, because the values the Pritzkers espouse align with our own values of service and investment in our communities.”

“Their generous gift will help us transform Pritzker Hall into a space for breakthroughs — a collaborative, modern teaching and research space befitting one of the top psychology departments in the United States.”

The tower was designed by celebrated Los Angeles architect Paul Revere Williams and completed in 1967. Work on seismic upgrades began in 2018 and the full renovation is expected to be completed this year.

Sork said the endowment created by the Pritzkers’ gift will strengthen the department’s ability to recruit and retain top-notch faculty and students, a crucial factor in maintaining its excellence. UCLA Psychology faculty are pursuing research in a wide range of areas, including anxiety and depression; substance abuse and addiction; human relationships; stress, resilience and health; neuroscience; and cognition and consciousness, all focusing on how to improve people’s daily lives.

“This gift will be of incalculable benefit to faculty, students and members of the community for many decades to come,” Sork said.

This article originally appeared in the UCLA Newsroom.

Chronic opioid treatment may raise risk of post-traumatic stress disorder, study finds

Senior author Michael Fanselow said the research suggests that chronic opioid use increases susceptibility to developing anxiety disorders. Photo credit: Reed Hutchinson/UCLA

While opioids are often prescribed to treat people with trauma-related pain, a new UCLA-led study suggests doctors should use caution before prescribing the drug to those they believe may experience severe stress in the future, in order to reduce the risk the patient will develop PTSD.

In the study, researchers administered doses of the opioid morphine to a group of 22 mice for one week, then gave the mice relatively strong foot shocks. After the morphine wore off, the mice were given mild electric foot shocks. These mice showed a substantially longer “freezing response” than a second, control group of 24 mice that had not been given morphine. When mice recall a frightening memory, they freeze. Their heart rates and blood pressure go up, and the more frightening the memory, the more they freeze.

“While we are generally aware that drug use, such as that in the current opioid crisis, has many deleterious effects, our results suggest yet another effect — increased susceptibility to developing anxiety disorders,” said senior author Michael Fanselow, UCLA distinguished Staglin family professor of psychology and director of UCLA’s Staglin Family Music Festival Center for Brain and Behavioral Health. “As opioids are often prescribed to treat symptoms such as pain that may accompany trauma, caution may be needed because this may lead to a greater risk of developing PTSD, if exposed to further traumatic events, such as an accident, later on.”

“The foot shocks produced lasting fear and anxiety-like behaviors, such as freezing,” Fanselow said.

“Our data are the first to show a possible effect of opioids on future fear learning, suggesting that a person with a history of opioid use may become more susceptible to the negative effects of stress,” Fanselow said. “The ability of opioids to increase PTSD-like symptoms far outlasted the direct effects of the drug or withdrawal from the drug, suggesting the effect may continue even after opioid treatment has stopped.”

Fanselow’s view is if there is reason to believe a patient is likely to experience severe emotional stress after opioid treatment, then doctors should use caution about prescribing an opioid. If opioid use is medically called for, then the patient should be kept away from potentially stressful situations. So, for example, a soldier treated with opioids for pain should not be sent back into combat for a period of time, he said. The development of post-traumatic stress disorder requires some stressful experience after opioid use, he said.

The researchers also gave some of the mice morphine after the initial trauma had occurred but before exposing them to the second, mild stressor. They found that mice treated with morphine after the initial trauma did not show enhanced fear learning following exposure to the mild stressor. This finding suggests that chronic use of opioids before — but not after — a traumatic event occurs affects fear learning during subsequent stressful events.

The researchers concluded the mice given morphine were more susceptible to post-traumatic stress disorder than the control group of mice not given any opioids, and inferred that people with a history of using opioids are more susceptible to PTSD than the general population.

The study is published in Neuropsychopharmacology, an international scientific journal focusing on clinical and basic science research that advances understanding of the brain and behavior.

The research was funded by the National Institute on Drug Abuse and National Institute of Mental Health.

An opiate is a drug naturally derived from the opium poppy plant, such as heroin, morphine and codeine. Opioid is a broader term that includes opiates and any substance, natural or synthetic, that binds to the brain’s opioid receptors — which play a key role in controlling pain, rewards and addictive behaviors. Synthetic opioids include the prescription painkillers Vicodin and OxyContin, as well as fentanyl and methadone.

Substance abuse and PTSD often go hand-in-hand, Fanselow said, and people with PTSD often take drugs to self-medicate. Nearly 40% of people with PTSD also have a drug disorder.

Fanselow and colleagues reported last month that a traumatic brain injury causes changes in a brain region called the amygdala; and the brain processes fear differently after such an injury.

This article originally appeared in the UCLA Newsroom.

Minds Matter: Raising the Curtain on Depression and Anxiety

Photo of Cleveland Cavaliers basketball player Kevin Love and UCLA College’s Clinical Psychology expert Michelle Craske.

Cleveland Cavaliers basketball player Kevin Love and UCLA College’s Clinical Psychology expert Michelle Craske.

UCLA students, community members and supporters joined Cleveland Cavaliers basketball player Kevin Love and UCLA College’s Clinical Psychology expert Michelle Craske for a standing-room only hybrid class and public lecture on Monday, August 19, for “Minds Matter: Raising the Curtain on Depression and Anxiety,” a free hour-long discussion on the causes of depression and anxiety, public stigma, and potential advances for the future. The series was the first in an ongoing exploration of brain health that will continue with additional events focusing on bullying, aging well, and other topics.

Love, an NBA Champion and five-time NBA All-Star for the Cleveland Cavaliers, has publicly discussed his struggle with panic attacks and anxiety and his decision to seek therapy, and has become a leading voice in mental health advocacy and founded the Kevin Love Fund in 2018 with the mission of inspiring people to live their healthiest lives while providing the tools to achieve physical and emotional well-being.

“Mental health isn’t just an athlete thing, it’s an issue that affects everyone in some way. The more we can normalize the conversation around mental health, the more we can do to help those that are struggling,” said Love. “My goal in sharing my personal experience is to connect with others who are going through something and keep this dialogue top of mind.”

Michelle G. Craske is a UCLA Professor of Psychology, Psychiatry and Biobehavioral Sciences, Director of the Anxiety and Depression Research Center, and Associate Director of the Staglin Family Music Center for Behavioral and Brain Health. Craske has published extensively in the area of fear, anxiety and depression.

“We need to work together to bring anxiety and depression out of the dark. People who suffer will only seek help when they can do so without fear of shame. Event series such as ‘Minds Matter’ aim to shed a light on these critical issues, and to help make a positive breakthrough,” said Craske.

Craske also is Director of the Innovative Treatment Network within the UCLA Depression Grand Challenge, a campus-wide effort to cut the global burden of depression in half. The innovative treatment component, which Craske leads, seeks to develop novel and more effective treatments for depression and anxiety and increase the scalability and accessibility of existing evidence-based treatments.

The “Minds Matter” series leverages the strengths of UCLA College’s Psychology faculty as well as high-profile guests who provide specialized insight about the discussion topic. Upcoming sessions will include discussions on addiction, adolescent brain development and behavior, bullying, healthy aging, and thriving under stress. The “Minds Matter” series is made possible through the longstanding UCLA College and Geffen Playhouse partnership and the generous support of donors.

Check back for information on future “Minds Matter” events at  https://www.college.ucla.edu/minds-matter/.

UCLA faculty voice: Separating children from parents at the border isn’t just cruel. It’s torture.

Children arriving at the U.S. border in search of asylum are frequently a particularly vulnerable population. In many cases fleeing violence and persecution, they also encounter hunger, illness and threats of physical harm along their hazardous journey to the border.

Where Are They Now: Andrew Nicholls

The Spring 2013 issue of the College Report magazine featured psychology major Andrew Nicholls’ military service and his veterans advocacy work at UCLA. We recently caught up with him to learn more about his post-graduate career path and current endeavors.

Having spent more than nine years in the U.S. Army, Andrew Nicholls ’13 draws on his personal experience and UCLA education to pursue mental health advocacy for veterans and help them with the transition to civilian life.

Nicholls works as a clinical care manager at Evergreen Health in Kirkland, WA, where he conducts assessments of mental health and assault risk as well as crisis prevention. He plans to return to the Veterans Affairs office in Seattle to continue his research on veterans’ mental health.

The terrorist attacks of September 11, 2001 prompted Nicholls to enlist in the military. While on active duty in Iraq he worked mainly on rebuilding community infrastructure and vocational programs. Unfortunately, his Army experience left him with lasting effects of PTSD, a struggle that led to his interest in veterans’ mental health advocacy.

Nicholls set his sights on UCLA and enrolled as a transfer student in 2011. He was named a UCLA Regents Scholar, honoring him as one of the top applicants of his class. He credits his mentor, psychology professor Christine Dunkel Schetter, with showing him how psychology research and social work could be a way to leverage his experience to help others.

“UCLA pushed me to challenge any notions I had of the status quo,” Nicholls said.

In 2012 while at UCLA, Nicholls founded the Killed in Action, Wounded in Action (KIA WIA) Foundation, which raises awareness of the sacrifices of men and women wounded or killed in the Global War on Terror. He also initiated an undergraduate seminar titled “Fast Cars and Battle Scars: Understanding the Modern Combat Veteran and PTSD,” which explored basic training, soldier perspectives and transition to civilian life. Nicholls said he was impressed by the depth with which the students engaged with the material, and he has stayed in touch with many of them.

“Leading that seminar was my top achievement while at UCLA,” he said. “Teaching reminded me of my time in the Army. What I loved about my experience in the military was leading a team and feeling a sense of comradery.”

After graduation, Nicholls continued to work for KIA WIA and obtained a master’s degree in social work from USC. He recently co-authored an article titled “Tattoos as a Window to the Psyche: How Talking about Skin Art Can Inform Psychiatric Practice due for publication in the World Journal of Psychology.

Infants show apparent awareness of ethnic differences, UCLA psychologists report

Infants less than a year old, who have yet to learn language, appear to notice differences when looking at adult women of different ethnicities, a new study by UCLA psychologists shows.

UCLA faculty voice: Body mass index perpetuates stigmas and indicates little about health

You’ve just returned from your morning run and you’re rustling through your snail mail when you receive some shocking news — an official memo from your employer informing you that your health insurance premium is increasing by 30 percent.

Q&A: UCLA psychologist Robert Bjork on the science of learning

Robert Bjork, Distinguished Research Professor in the UCLA Department of Psychology, will share insights from his work as a renowned expert on human learning in the 120th Faculty Research Lecture, “How We Learn Versus How We Think We Learn.”

Don’t use body mass index to determine whether people are healthy, UCLA-led study says

Over the past few years, body mass index, a ratio of a person’s height and weight, has effectively become a proxy for whether a person is considered healthy. Many U.S. companies use their employees’ BMIs as a factor in determining workers’ health care costs.

Is seeing believing? People are surprisingly bad at identifying where sights and sounds originate

“We tend to view our senses as flawless and think that to see is to believe,” she said. “So it’s eye-opening to learn that our perceptions are flawed.”