Image of Kabuki actor performing

UCLA receives $25 million from Uniqlo founder for Japanese literature and culture studies

Image of Kabuki actor performing

Renowned Kabuki actor Nakamura Kyozo performing the role of a lion in “Shujaku jishi” at the Glorya Kaufman Dance Theater in an event for students co-sponsored by the Yanai Initiative and the Japanese Ministry of Culture (November 14, 2019). (Credit: Ning Wong Studios)

UCLA has received a $25 million gift from Tadashi Yanai, the chair, president and CEO of Japan-based Fast Retailing and founder of clothing company Uniqlo. The funds will endow the Tadashi Yanai Initiative for Globalizing Japanese Humanities, which will bolster UCLA’s status as a leading center for the study of Japanese literature, language and culture.

The gift is the largest from an individual donor in the history of the UCLA College’s humanities division. A previous donation of $2.5 million from Yanai in 2014 created the Yanai Initiative, a collaboration between UCLA and Waseda University, one of Japan’s most prestigious universities. The program supports academic and cultural programming and enables student and faculty exchanges between the two universities. This latest gift will ensure the initiative’s long-term future.

“Mr. Yanai’s extraordinary gifts are a testament to UCLA’s long-standing commitment to educate global citizens who can thrive in careers — and cultures — anywhere in the world,” said UCLA Chancellor Gene Block. “The Tadashi Yanai Initiative for Globalizing Japanese Humanities will have a profound and lasting impact on this campus.”

Photo of Tadashi Yanai

UCLA has received a $25 million gift from Tadashi Yanai, the chair, president and CEO of Japan-based Fast Retailing and founder of clothing company Uniqlo. (Credit: Fast Retailing Co., Ltd.)

The Yanai Initiative is housed in the UCLA College department of Asian languages and cultures and directed by Professor Michael Emmerich. The latest gift will fund and establish an endowed chair in Japanese literature and will fund conferences, public lectures, faculty research, cultural performances and community outreach. It will support graduate and postdoctoral fellowships and undergraduate awards.

“It has been inspiring to see all of the creative, innovative programming — both academic and cultural — that this project has realized over the past five years,” Yanai said. “Now that we are making it permanent, I’m excited to see how it will continue to transform the Japanese humanities in a global context. At the same time, I hope this gift will give others a chance to remember how crucial the humanities are, and, in their own way, to recommit.”

The gift also triggers matching funds from the Humanities Centennial Match and the UCLA Centennial Scholars Match to support UCLA graduate students in Japanese humanities and other areas of study.

“Mr. Yanai’s gift is a visionary investment in a field of increasing interest to humanities scholars, students and people everywhere,” said David Schaberg, UCLA’s dean of humanities. “Thanks to his generosity, UCLA will lead the way in research and teaching in Japanese humanities, bringing new attention to a rich culture that has captured people’s imaginations for centuries.”

Schaberg said another benefit of the gift is that it will deepen UCLA’s partnership with Waseda.

In addition to funding fellowships, symposia, lectures and academic workshops, Yanai’s previous donation supported a range of cultural programs, including a five-day series of events featuring actor Nomura Mansaku, who was designated a “living national treasure” by the Japanese government; a retrospective of films by Palme d’Or recipient Hirokazu Kore-eda; and “The Art of the Benshi,” which introduced Los Angeles audiences to the early 20th century performance art in which narrators bring silent movies to life with live music accompaniment.

“During the past five years, Mr. Yanai’s generosity has enabled us to do so much for students and for the Japanese humanities not just at UCLA, but across the country and around the world,” Emmerich said. “We’ve been able to organize major cultural events across Los Angeles, drawing thousands of participants. I never imagined I would be able to say that all this was only the beginning. I can’t express how grateful we all are to Mr. Yanai for his generosity, his incisive advice and his commitment.”

The gift was facilitated through a designated donations program run by the Japan Foundation, which is dedicated to promoting cultural and intellectual exchange with Japan. Over the past three decades, the foundation has helped advance and fund numerous cultural programs at UCLA.

View this release in Japanese

Unearthing Easter Island’s Moai

Two Moai are shown during excavations by Jo Anne Van Tilburg and her team at Rano Raraku quarry on Rapa Nui, better known as Easter Island. Photo credit: Easter Island Statue Project

Rapa Nui (or Easter Island, as it is commonly known) is home to the enigmatic Moai, stone monoliths that have stood watch over the island landscape for hundreds of years. Their existence is a marvel of human ingenuity — and their meaning a source of some mystery.

Ancient Rapanui carvers worked at the behest of the elite ruling class to carve nearly 1,000 Moai because they, and the community at large, believed the statues capable of producing agricultural fertility and thereby critical food supplies, according to a new study from Jo Anne Van Tilburg, director of the Easter Island Statue Project, recently published in Journal of Archaeological Science.

Van Tilburg and her team, working with geoarchaeologist and soils specialist Sarah Sherwood, believe they have found scientific evidence of that long-hypothesized meaning thanks to careful study of two particular Moai excavated over five years in the Rano Raraku quarry on the eastern side of the Polynesian island.

Van Tilburg’s most recent analysis focused on two of the monoliths that stand within the inner region of the Rano Raraku quarry, which is the origin of 95 percent of the island’s more than 1,000 Moai. Extensive laboratory testing of soil samples from the same area shows evidence of foods such as banana, taro and sweet potato.

Van Tilburg said the analysis showed that in addition to serving as a quarry and a place for carving statues, Rano Raraku also was the site of a productive agricultural area.

“Our excavation broadens our perspective of the Moai and encourages us to realize that nothing, no matter how obvious, is ever exactly as it seems. I think our new analysis humanizes the production process of the Moai,” Van Tilburg said.

Van Tilburg has been working on Rapa Nui for more than three decades. Her Easter Island Statue Project is supported in part by UCLA’s Cotsen Institute of Archaeology. Tom Wake, a Cotsen Institute colleague, analyzes small-animal remains from the excavation site. Van Tilburg also serves as director of UCLA’s Rock Art Archive.

Van Tilburg, in partnership with members of the local community, heads the first legally permitted excavations of Moai in Rano Raraku since 1955. Cristián Arévalo Pakarati, a noted Rapanui artist, is project co-director.

The soils in Rano Raraku are probably the richest on the island, certainly over the long term, Sherwood said. Coupled with a fresh-water source in the quarry, it appears the practice of quarrying itself helped boost soil fertility and food production in the immediate surroundings, she said. The soils in the quarry are rich in clay created by the weathering of lapilli tuff (the local bedrock) as the workers quarried into deeper rock and sculpted the Moai.

A professor of earth and environmental systems at the University of the South in Sewanee, Tenn., Sherwood joined the Easter Island Project after meeting another member of Van Tilburg’s team at a geology conference.

She wasn’t originally looking for soil fertility, but out of curiosity and research habit, she did some fine-scale testing of samples brought back from the quarry.

“When we got the chemistry results back, I did a double take,” Sherwood said. “There were really high levels of things that I never would have thought would be there, such as calcium and phosphorous. The soil chemistry showed high levels of elements that are key to plant growth and essential for high yields. Everywhere else on the island the soil was being quickly worn out, eroding, being leeched of elements that feed plants, but in the quarry, with its constant new influx of small fragments of the bedrock generated by the quarrying process, there is a perfect feedback system of water, natural fertilizer and nutrients.”

She said it also looks like the ancient indigenous people of Rapanui were very intuitive about what to grow — planting multiple crops in the same area, which can help maintain soil fertility.

The Moai that Van Tilburg’s team excavated were discovered upright in place, one on a pedestal and the other in a deep hole, indicating they were meant to remain there.

“This study radically alters the idea that all standing statues in Rano Raraku were simply awaiting transport out of the quarry,” Van Tilburg said. “That is, these and probably other upright Moai in Rano Raraku were retained in place to ensure the sacred nature of the quarry itself. The Moai were central to the idea of fertility, and in Rapanui belief their presence here stimulated agricultural food production.”

Van Tilburg and her team estimate the statues from the inner quarry were raised by or before A.D. 1510 to A.D.1645. Activity in this part of the quarry most likely began in A.D.1455. Most production of Moai had ceased in the early 1700s due to western contact.

The two statues Van Tilburg’s team excavated had been almost completely buried by soils and rubble.

“We chose the statues for excavation based on careful scrutiny of historical photographs and mapped the entire Rano Raraku inner region before initiating excavations,” she said.

Van Tilburg has worked hard to establish connections with the local community on Rapa Nui. The project’s field and lab teams are made up of local workers, mentored by professional archeologists and geologists.

The result of their collective efforts is a massive detailed archive and comparative database that documents more than 1,000 sculptural objects on Rapa Nui, including the Moai, as well as similar records on more than 200 objects scattered in museums throughout the world. In 1995, UNESCO named Easter Island a World Heritage Site, with most of the island’s sacred sites protected within Rapa Nui National Park.

This is the first definitive study to reveal the quarry as a complex landscape and to make a definitive statement that links soil fertility, agriculture, quarrying and the sacred nature of the Moai.

Van Tilburg and her team are working on another study that analyzes the rock art carvings that exist on only three of the Moai.

This article originally appeared in the UCLA Newsroom.

That Supermassive Black Hole in our Galaxy? It has a Friend.

Two black holes are entwined in a gravitational tango in this artist’s conception. Photo Credit: NASA/JPL-Caltech/SwRI/MSSS/Christopher Go

Smadar Naoz is an associate professor of physics and astronomy in the UCLA College. She wrote this article for The Conversation.

Do supermassive black holes have friends? The nature of galaxy formation suggests that the answer is yes, and in fact, pairs of supermassive black holes should be common in the universe.

I am an astrophysicist and am interested in a wide range of theoretical problems in astrophysics, from the formation of the very first galaxies to the gravitational interactions of black holes, stars and even planets. Black holes are intriguing systems, and supermassive black holes and the dense stellar environments that surround them represent one of the most extreme places in our universe.

The supermassive black hole that lurks at the center of our galaxy, called Sgr A*, has a mass of about 4 million times that of our sun. A black hole is a place in space where gravity is so strong that neither particles or light can escape from it. Surrounding Sgr A* is a dense cluster of stars. Precise measurements of the orbits of these stars allowed astronomers to confirm the existence of this supermassive black hole and to measure its mass. For more than 20 years, scientists have been monitoring the orbits of these stars around the supermassive black hole. Based on what we’ve seen, my colleagues and I show that if there is a friend there, it might be a second black hole nearby that is at least 100,000 times the mass of the sun.

Supermassive black holes and their friends

Almost every galaxy, including our Milky Way, has a supermassive black hole at its heart, with masses of millions to billions of times the mass of the sun. Astronomers are still studying why the heart of galaxies often hosts a supermassive black hole. One popular idea connects to the possibility that supermassive holes have friends.

To understand this idea, we need to go back to when the universe was about 100 million years old, to the era of the very first galaxies. They were much smaller than today’s galaxies, about 10,000 or more times less massive than the Milky Way. Within these early galaxies the very first stars that died created black holes, of about tens to thousand the mass of the sun. These black holes sank to the center of gravity, the heart of their host galaxy. Since galaxies evolve by merging and colliding with one another, collisions between galaxies will result in supermassive black hole pairs – the key part of this story. The black holes then collide and grow in size as well. A black hole that is more than a million times the mass of our sun is considered supermassive.

If indeed the supermassive black hole has a friend revolving around it in close orbit, the center of the galaxy is locked in a complex dance. The partners’ gravitational tugs will also exert its own pull on the nearby stars disturbing their orbits. The two supermassive black holes are orbiting each other, and at the same time, each is exerting its own pull on the stars around it.

The gravitational forces from the black holes pull on these stars and make them change their orbit; in other words, after one revolution around the supermassive black hole pair, a star will not go exactly back to the point at which it began.

Using our understanding of the gravitational interaction between the possible supermassive black hole pair and the surrounding stars, astronomers can predict what will happen to stars. Astrophysicists like my colleagues and me can compare our predictions to observations, and then can determine the possible orbits of stars and figure out whether the supermassive black hole has a companion that is exerting gravitational influence.

Using a well-studied star, called S0-2, which orbits the supermassive black hole that lies at the center of the galaxy every 16 years, we can already rule out the idea that there is a second supermassive black hole with mass above 100,000 times the mass of the sun and farther than about 200 times the distance between the sun and the Earth. If there was such a companion, then I and my colleagues would have detected its effects on the orbit of SO-2.

But that doesn’t mean that a smaller companion black hole cannot still hide there. Such an object may not alter the orbit of SO-2 in a way we can easily measure.

The physics of supermassive black holes

Supermassive black holes have gotten a lot of attention lately. In particular, the recent image of such a giant at the center of the galaxy M87 opened a new window to understanding the physics behind black holes.

The proximity of the Milky Way’s galactic center – a mere 24,000 light-years away – provides a unique laboratory for addressing issues in the fundamental physics of supermassive black holes. For example, astrophysicists like myself would like to understand their impact on the central regions of galaxies and their role in galaxy formation and evolution. The detection of a pair of supermassive black holes in the galactic center would indicate that the Milky Way merged with another, possibly small, galaxy at some time in the past.

That’s not all that monitoring the surrounding stars can tell us. Measurements of the star S0-2 allowed scientists to carry out a unique test of Einstein’s general theory of relativity. In May 2018, S0-2 zoomed past the supermassive black hole at a distance of only about 130 times the Earth’s distance from the sun. According to Einstein’s theory, the wavelength of light emitted by the star should stretch as it climbs from the deep gravitational well of the supermassive black hole.

The stretching wavelength that Einstein predicted – which makes the star appear redder – was detected and proves that the theory of general relativity accurately describes the physics in this extreme gravitational zone. I am eagerly awaiting the second closest approach of S0-2, which will occur in about 16 years, because astrophysicists like myself will be able to test more of Einstein’s predictions about general relativity, including the change of the orientation of the stars’ elongated orbit. But if the supermassive black hole has a partner, this could alter the expected result.

Finally, if there are two massive black holes orbiting each other at the galactic center, as my team suggests is possible, they will emit gravitational waves. Since 2015, the LIGO-Virgo observatories have been detecting gravitational wave radiation from merging stellar-mass black holes and neutron stars. These groundbreaking detections have opened a new way for scientists to sense the universe.

Any waves emitted by our hypothetical black hole pair will be at low frequencies, too low for the LIGO-Virgo detectors to sense. But a planned space-based detector known as LISA may be able to detect these waves which will help astrophysicists figure out whether our galactic center black hole is alone or has a partner.

This article originally appeared in the UCLA Newsroom.

Top Stories from 2019

UCLA College often featured in the news during 2019: from discoveries about health, the environment and the Universe, to research and engagement that are helping to move society forward. Here are some of the top stories of the year.

Science and technology

 

 

 

 

 

 

Einstein’s general relativity theory questioned, but still stands ‘for now’

A detailed analysis of a star’s orbit near a supermassive black hole gives a look into how gravity behaves.

 

 

 

 

 

 

Ancient stars shed light on Earth’s similarities to other planets

A new method used to study planets’ geochemistry implies that Earth is not unique.

 

 

 

 

 

 

New device creates electricity from snowfall

Researchers have designed a nanogenerator that can work in remote areas on its own power — and acts as a weather station.

Health and behavior

 

 

 

 

 

 

 

Biochemists discover new insights into what may go awry in brains of people with Alzheimer’s

The findings could lead to new methods to get the body’s repair enzyme to work better.

 

 

 

 

 

 

 

 

A small electrical zap to the brain could help you retrieve a forgotten memory

Professor found that the left rostrolateral prefrontal cortex is important in accessing knowledge that was formed in the past and making decisions about it.

Students and campus

 

 

 

 

 

 

‘Pink tax’ activists made the most of their UCLA experience

Twin sisters Helen and Rachel Lee have dedicated themselves to repeal of the sales tax on feminine hygiene products.

 

 

 

 

 

 

Graduate helps victims of Syrian war ‘rise again’

Haya Kaliounji founded the non-profit, Rise Again, which provides people wounded in the conflict in her home country with free prosthetic limbs.

Environment and climate

 

 

 

 

 

 

Arctic Ocean could be ice-free for part of the year as soon as 2044

UCLA study finds the ominous change could happen earlier than previously thought.

 

 

 

 

 

 

UCLA experts are studying how the Woolsey fire affects plant and animal recovery

Research teams closely monitor the Santa Monica Mountains to examine impacts throughout the food chain.

 

 

 

 

 

 

UCLA aflutter over the butterfly effect

Why there were so many painted lady butterflies in Southern California this year.

Nation, world and society

 

 

 

 

 

 

Unearthing the mystery of the meaning of Easter Island’s Moai

The Rapanui people most likely believed the ancient monoliths helped food to grow on the Polynesian island.

 

 

 

 

 

 

Political scientists launch one of largest-ever public opinion surveys

As the nation heads into another contentious presidential campaign, UCLA will study what drives voters’ choices in 2020.

Arts and culture

 

 

 

 

 

 

 

Hollywood Diversity Report finds bright spots for women and minorities

“We feel confident our partners in Hollywood today see the value of diversity in ways that they did not before,” said Darnell Hunt, dean of the UCLA College Division of Social Sciences.

Faculty and staff

 

 

 

 

 

 

Historian Kelly Lytle Hernández awarded MacArthur Fellowship

The renowned scholar of race, mass incarceration and immigration said she will continue to expand her social justice work.

Rankings headlines

 

 

 

 

 

 

UCLA named No. 1 U.S. public institution by U.S. News & World Report for third consecutive year

 

 

 

 

 

 

UCLA is No. 1 public college in 2020 Wall Street Journal/Times Higher Education ranking

Photograph of Sarah Abrevaya Stein

Professor’s book about Sephardic Jews chosen as a best of 2019

Photograph of Sarah Abrevaya Stein

Sarah Abrevaya Stein. Photo credit: Caroline Libresco

Adding to the chorus of critics’ raves, The Economist has named “Family Papers: A Sephardic Journey Through the Twentieth Century,” a new book from UCLA professor of history Sarah Abrevaya Stein, to its best of 2019 list.

Stein’s latest work explores the intertwined histories of a single family (the Levys), Sephardic Jewry, and the dramatic ruptures that transformed southeastern Europe and the Judeo-Spanish diaspora. It has received glowing reviews from The New York Times, the Wall Street Journal (subscription required), the Los Angeles Review of Books and more.

Stein, who holds the Maurice Amado Endowed Chair in Sephardic Studies at UCLA, spent a decade researching this work, a journey that took her to a dozen countries, dozens of archives, and into the homes of a Sephardic clan that constituted its own, remarkable global diaspora.

The phrase “Sephardic Jew” refers to those of Spanish or Hispanic background. Stein’s new book begins with a family originally from old Salonica, a Mediterranean seaport of the Ottoman Empire, now Thessaloniki, Greece. In the late 19th century it was home to a large community of Spanish Jews.

The idea to tell the story of the Levy family came as Stein researched another book, an English-language translation of the first Ladino (which refers to a background of mixed Spanish, Latin American or Central American heritage) memoir ever written, “A Jewish Voice from Ottoman Salonica: The Ladino Memoir of Sa’adi Besalel A-Levi.”

“He spent the last years of his life writing a Ladino-language memoir to air a lifetime’s worth of grievances,” said Stein, who is also the Sady and Ludwig Kahn Director of the Alan D. Leve Center for Jewish Studies at UCLA.

Her book traces the history of a collection, how one family archive came to be built and preserved.

The existence of Sa’adi’s personal memoir, one sole copy written in written in soletreo (the unique handwritten cursive of Ladino), outlived wars; the collapse of the empire in which it was conceived; a major fire in Salonica; and the Holocaust, during which Jewish texts and libraries as well as Jewish bodies were targeted by the Nazis for annihilation.

Stein was fascinated by the fact that this manuscript passed through four generations of Sa’adi’s family, traveling from Salonica to Paris, from there to Rio de Janeiro and, finally, to Jerusalem.

“It somehow eluded destruction or disappearance despite the collapse of the Salonican Jewish community and the dispersal of the author’s descendants over multiple countries and continents,” she said. “It knit together a family even as the historic Sephardi heartland of southeastern Europe was unraveling.”

Stein’s book traces decades of family correspondence and shared memories to reveal what became of Sa’adi’s 14 children and their far-flung descendants. Most fled Salonica after the collapse of the Ottoman Empire, or attempted to flee later in 20th Century, when 37 members of the Levy family perished in the Holocaust.

This article originally appeared in the UCLA Newsroom.

Photograph of homeless tent encampment.

L.A. could better target homeless prevention services with predictive analytics

Photograph of homeless tent encampment.

Photo credit: California Policy Lab

Each year, 2 million single adults receive housing, health, and emergency services from Los Angeles County. About 2% of them — around 76,000 people — will become homeless. Predictive modeling could help address the homelessness crisis in Los Angeles County, according to a report by researchers from the California Policy Lab at UCLA, and the Poverty Lab at the University of Chicago Harris School of Public Policy.

Using data from seven Los Angeles County agencies about services they provided to county residents between 2012 and 2016 — the residents’ names and personally identifiable information were omitted and each person was assigned an ID number for the study — researchers developed a model to predict which 3,000 residents were most likely to become homeless in 2017.

The researchers then checked the accuracy of their predictions against county records, and found that 46% of the people predicted by the model to be at risk for first-time homelessness or a repeat spell of homelessness did in fact become homeless at some point during 2017.

“Bringing together data from multiple county agencies gave us a more nuanced understanding about what’s happening to people right before they slip into homeless and how services can be better targeted to prevent that from happening,” said Till von Wachter, a UCLA economics professor and co-author of the report.  Von Wachter is also faculty director at the California Policy Lab.

The California Policy Lab pairs UCLA and other UC researchers with policymakers to solve urgent social problems, including homelessness, poverty, crime and education inequality.

The research informed an action plan that was developed by the county-led Mainstream Systems Homelessness Prevention Workgroup. That plan, which was submitted to the Los Angeles County Board of Supervisors on Dec. 16, recommends that the county use predictive models to intervene with adults who are identified as having a high risk for homelessness before they reach a crisis.

It also suggests that the county launch a multidisciplinary homelessness prevention unit that includes representatives of the county’s departments of mental health, health services and social services, and the sheriff and probation offices. The unit would accept referrals from the risks lists generated by the predictive models, identify which programs or services would be most helpful for each individual, and then reach out to people to connect them to those services.

The plan is expected to receive $3 million in funding during 2020 from Measure H, a sales tax approved by Los Angeles County voters in 2017 to help address the homeless crisis, in addition to drawing some existing resources from Los Angeles County departments.

“Last year, despite providing housing to tens of thousands of people, we saw more and more individuals and families becoming homeless,” said Phil Ansell, the director of the Los Angeles County Homeless Initiative. “The county is focused on using strategic approaches to preventing homelessness, and these groundbreaking models will make it possible to reach those who need us the most before they reach the crisis point and fall into homelessness.”

The models allowed researches to identify warning signs that could help local governments intervene early, especially for residents living in deep poverty, said Harold Pollack, the Helen Ross Professor at the University of Chicago School of Social Service Administration and a co-author of the study. The research that led to the new recommendations was begun at Chicago.

“The models suggest that sharp spikes in service use, increasingly frequent service use and the receipt of multiple services from a single agency are all warning signs that someone is at high risk for homelessness,” Pollack said. “We’re now diving deeper into the models with our Los Angeles County partners to learn more and to see how these results can help focus public health and social services to this vulnerable population.”

Janey Rountree, executive director of the California Policy Lab at UCLA, said using the predictive models could go a long way toward making sure homeless prevention services reach the right people at the right time.

“Predictive modeling can help ensure that happens, before they’re in a full-blown crisis,” she said. “We look forward to seeing its impact in connecting people to the help they need.”

The study also found:

  • Effectively serving the 1% of county clients who have the greatest risk for a new homeless spell would prevent nearly 6,900 homeless spells in one year.
  • County residents who have the highest risk for homelessness are interacting with multiple agencies.
  • Falling into homelessness happens very quickly, typically within six months of a precipitating event, meaning that Los Angeles County and service providers must react quickly.

The research was provided at no cost to the county. Financial support was provided by Arnold Ventures and the Max Factor Family Foundation.

This article originally appeared in the UCLA Newsroom.

Chronic opioid treatment may raise risk of post-traumatic stress disorder, study finds

Senior author Michael Fanselow said the research suggests that chronic opioid use increases susceptibility to developing anxiety disorders. Photo credit: Reed Hutchinson/UCLA

While opioids are often prescribed to treat people with trauma-related pain, a new UCLA-led study suggests doctors should use caution before prescribing the drug to those they believe may experience severe stress in the future, in order to reduce the risk the patient will develop PTSD.

In the study, researchers administered doses of the opioid morphine to a group of 22 mice for one week, then gave the mice relatively strong foot shocks. After the morphine wore off, the mice were given mild electric foot shocks. These mice showed a substantially longer “freezing response” than a second, control group of 24 mice that had not been given morphine. When mice recall a frightening memory, they freeze. Their heart rates and blood pressure go up, and the more frightening the memory, the more they freeze.

“While we are generally aware that drug use, such as that in the current opioid crisis, has many deleterious effects, our results suggest yet another effect — increased susceptibility to developing anxiety disorders,” said senior author Michael Fanselow, UCLA distinguished Staglin family professor of psychology and director of UCLA’s Staglin Family Music Festival Center for Brain and Behavioral Health. “As opioids are often prescribed to treat symptoms such as pain that may accompany trauma, caution may be needed because this may lead to a greater risk of developing PTSD, if exposed to further traumatic events, such as an accident, later on.”

“The foot shocks produced lasting fear and anxiety-like behaviors, such as freezing,” Fanselow said.

“Our data are the first to show a possible effect of opioids on future fear learning, suggesting that a person with a history of opioid use may become more susceptible to the negative effects of stress,” Fanselow said. “The ability of opioids to increase PTSD-like symptoms far outlasted the direct effects of the drug or withdrawal from the drug, suggesting the effect may continue even after opioid treatment has stopped.”

Fanselow’s view is if there is reason to believe a patient is likely to experience severe emotional stress after opioid treatment, then doctors should use caution about prescribing an opioid. If opioid use is medically called for, then the patient should be kept away from potentially stressful situations. So, for example, a soldier treated with opioids for pain should not be sent back into combat for a period of time, he said. The development of post-traumatic stress disorder requires some stressful experience after opioid use, he said.

The researchers also gave some of the mice morphine after the initial trauma had occurred but before exposing them to the second, mild stressor. They found that mice treated with morphine after the initial trauma did not show enhanced fear learning following exposure to the mild stressor. This finding suggests that chronic use of opioids before — but not after — a traumatic event occurs affects fear learning during subsequent stressful events.

The researchers concluded the mice given morphine were more susceptible to post-traumatic stress disorder than the control group of mice not given any opioids, and inferred that people with a history of using opioids are more susceptible to PTSD than the general population.

The study is published in Neuropsychopharmacology, an international scientific journal focusing on clinical and basic science research that advances understanding of the brain and behavior.

The research was funded by the National Institute on Drug Abuse and National Institute of Mental Health.

An opiate is a drug naturally derived from the opium poppy plant, such as heroin, morphine and codeine. Opioid is a broader term that includes opiates and any substance, natural or synthetic, that binds to the brain’s opioid receptors — which play a key role in controlling pain, rewards and addictive behaviors. Synthetic opioids include the prescription painkillers Vicodin and OxyContin, as well as fentanyl and methadone.

Substance abuse and PTSD often go hand-in-hand, Fanselow said, and people with PTSD often take drugs to self-medicate. Nearly 40% of people with PTSD also have a drug disorder.

Fanselow and colleagues reported last month that a traumatic brain injury causes changes in a brain region called the amygdala; and the brain processes fear differently after such an injury.

This article originally appeared in the UCLA Newsroom.

Image of interstellar comet.

New NASA image provides more details about first observed interstellar comet

Image of interstellar comet.

The interstellar comet Comet 2I/Borisov (blueish image at right) near a spiral galaxy (left), in an image taken Nov. 16. Photo credit: NASA, ESA and David Jewitt/UCLA

A new image from NASA’s Hubble Space Telescope provides important new details about the first interstellar comet astronomers have seen in our solar system.

The comet, called Comet 2I/Borisov (the “I” stands for interstellar), was spotted near a spiral galaxy known as 2MASX J10500165-0152029. It was approximately 203 million miles from Earth when the image was taken on Nov. 16.

“Data from the Hubble Space Telescope give us the best measure of the size of comet 2I/Borisov’s nucleus, which is the really important part of the comet,” said David Jewitt, a UCLA professor of planetary science and astronomy who analyzed and interpreted the data from the new image.

Jewitt collaborated on the new analysis with colleagues from the University of Hawaii, Germany’s Max Planck Institute for Solar System Research, the Space Telescope Science Institute in Baltimore and Johns Hopkins University’s Applied Physics Laboratory. The scientists were surprised to learn that the nucleus has a radius measuring only about half of a kilometer — or less than one-fifteenth the size that earlier investigations suggested it might be.

“That is important because knowing its size helps us to determine the total number, and mass, of other similar objects in the solar system and the Milky Way,” Jewitt said. “2I/Borisov is the first known interstellar comet, and we would like to learn how many others there are.”

The comet is traveling at a breathtaking speed of 110,000 miles per hour — one of the fastest comets ever seen, Jewitt said. More commonly, comets travel at about half that speed.

Crimean astronomer Gennady Borisov discovered the comet on Aug. 30, using a telescope he built. Based on precise measurements of its changing position, the International Astronomical Union’s Minor Planet Center calculated a likely orbit for the comet, which shows that it came from elsewhere in the galaxy. Jewitt said its precise point of origin is unknown.

A second Hubble Space Telescope image of the comet, taken on Dec. 9, shows the comet even closer to Earth, approximately 185 million miles from Earth, he said.

Comets are icy bodies thought to be fragments left behind when planets form in the outer parts of planetary systems.

Observations by numerous telescopes show that the comet’s chemical composition is similar to that of comets previously observed in our solar system, which provides evidence that comets also form around other stars, Jewitt said. By mid-2020, the comet will have zoomed past Jupiter on its way back into interstellar space, where it will drift for billions of years, Jewitt said.

This article originally appeared in the UCLA Newsroom.

Photo of student smiling.

Meet UCLA Student Researcher Julia Nakamura

Photo of student smiling.

Fourth-year UCLA student researcher Julia Nakamura

Meet fourth-year UCLA student researcher Julia Nakamura!

Julia majors in Psychobiology with a minor in Gerontology and is in our Undergraduate Research Scholars Program. The title of her research project is “The Role of Social Support in the Association between Early Life Stress, Depression, and Inflammation in Older Adults.”

 

How did you first get interested in your research project?

UCLA’s Cluster course “Frontiers in Human Aging” initially sparked my interest in aging populations. Through a service learning project at ONEgeneration Adult Day Care Center, I directly witnessed the burden of chronic disease in later-life adults and realized the pressing need to understand the mechanisms underlying these adverse health outcomes. Through my coursework in psychology, I became interested in the psychological factors that influence biological mechanisms and have the potential to positively impact the trajectory of chronic disease outcomes.

I began research in psychology in Dr. Julienne Bower’s Mind-Body Lab under the direction of Dr. Kate Kuhlman. We study the effects of childhood adversity on biological and behavioral responses to psychological stress. My experiences in this lab led me to wonder what factors could mitigate adverse physical and mental health outcomes from stressful experiences, specifically in older adults. My honors research project examines if social support moderates the relationship between early-life stress, depressive symptoms, and inflammation in older adults using data from the Health and Retirement Study.

What has been the most exciting aspect of your research so far?

Getting to test my own research questions has been the best part of this project. Specifically, it has been really exciting for me to run my own data analyses for the first time with Dr. Kuhlman’s guidance. Experiencing the “behind-the-scenes” of research and systematically moving through the steps of conducting an independent project has been really informative. This project has helped me to feel that I am truly developing the skill set of an independent researcher, which is very exciting!

What has surprised you about your research or the research process?

The immensely collaborative nature of research in academia was quite surprising to me when I first started on this project. Through my research, I’ve had the privilege of working with several scientists and professors who are experts in their respective areas of study. They have all welcomed me and helped to make my project as scientifically sound and comprehensive as possible. Research really builds on itself. Learning from other people’s projects and ideas, even if they are outside of your immediate area of study, can result in high levels of collaboration and really interesting research!

What is one piece of advice you have for other UCLA students thinking about doing research?

I would advise students interested in research to actively pursue research opportunities. There are plenty of amazing opportunities to be involved in research at UCLA, but you have to seek them out. It can be intimidating to take the initial steps to reach out to professors and discuss their research interests, but it is so worthwhile to find a lab and professor that are a good fit! I would recommend that students find an area of study that they are really passionate about. I think that your passion for your area of study and your continued curiosity will drive your research questions and help you get the most out of each research experience.

What effect do you hope your research has in your field, at UCLA, in your community, or in the world?

I hope to spend my life contributing to our understanding of the biobehavioral processes that promote mental and physical health across the lifespan. As the number of older adults (a majority of whom have at least one chronic disease) increase in our society, it is now more important than ever to identify potential intervention targets that can improve the trajectory of chronic disease outcomes.

This article originally appeared on the Undergraduate Research Center website.

Picture of a valley oak tree.

One of California’s iconic tree species offers lessons for conservation

Picture of a valley oak tree.

The valley oak, the largest oak in California, grows to over 100 feet tall and provides habitat and food for a variety of animals. Photo credit: Victoria Sork/UCLA

 

With increasing regularity, Californians are witnessing firsthand the destructive power of wildfires. But not everyone sees what happens after the flames die down, when debris is cleared, homes and lives rebuilt — and trees replanted to help nature recover.

New research led by UCLA evolutionary biologist Victoria Sork examines whether the trees being replanted in the wake of California’s fires will be able to survive a climate that is continuing to warm.

The study, which is published in the Proceedings of the Natural Academy of Sciences, focuses on California’s iconic valley oak. The research is among the first to demonstrate the potential of using genomics to inform conservation strategies — essentially giving species an evolutionary boost. The study showed that planting trees that are genetically better suited to higher temperatures makes them more likely to survive and grow to maturity.

“When we think about managing ecosystems under rapidly changing climates, we have to realize trees need to be able to survive past 50 years,” Sork said.

The paper also discovered something surprising: The valley oak, an essential component of many ecosystems in California, is already poorly adapted to its environment — even considering climate conditions in 2019.

“They actually seem to grow better in cooler climates than they’re in right now,” said Luke Browne, a postdoctoral scholar at the UCLA La Kretz Center for California Conservation Science and the study’s lead author. “They might grow better if climates were more like they were 21,000 years ago, during the last ice age.”

During the peak of the last ice age, summer temperatures were about 4 to 5 degrees Celsius colder, and ice covered most of Canada and mountainous areas of the U.S.

In the fields of conservation and land management, it is a common assumption that plants and animals are adapted to their environments — that’s how evolution and natural selection are supposed to work. The new research casts doubt on that assumption.

The study is part of an ongoing project initiated by Sork and Jessica Wright, an expert in conservation genetics at the USDA Forest Service, more than 10 years ago.

Researchers gathered 11,000 seeds from 94 locations throughout the trees’ range, which stretches from the Santa Monica Mountains to the Cascade foothills in the northern part of the state. They grew them to saplings in a greenhouse and planted them in two large experimental gardens, in Chico and Placerville, California. They tracked how well trees from different locations grew, and sequenced the genomes of their mother trees to link genetic information and growth rates.

The researchers then identified which genetic variants would be more likely to thrive as climate change continues to warm California. They predicted that, under predicted future warmer temperatures, trees containing beneficial genetic variations would have 11% higher growth rates than the average for all of the trees in the experiment, and 25% higher growth rates than the trees without the beneficial variations.

Information like that could help the U.S. Forest Service, for example, in its efforts to restore forests with species that have the best chance for long-term survival.

“Studies like this one provide valuable insights that help land managers make informed decisions on reforestation projects,” Wright said. “When planting trees in a particular location, managers have to decide where to collect the acorns.”

By 2070, average temperatures in the state are projected to be up to 4.8 degrees warmer than they were during the mid- to late 20th century.

“That’s going to have consequences for how fast these trees grow,” Browne said. “We’re at a challenging time to figure out the best way to do conservation science. This paper shows one approach we could use that takes advantage of modern genomics.”

The study did not determine why valley oaks are not well adapted to their environment. It might be because the climate has already warmed up so much, the trees’ long lifespans — up to 500 years — or some other, unknown factor.

The valley oak is the largest oak in California; it grows to over 100 feet tall, and has dark green leaves and a deeply grooved trunk. It is considered a foundational species because it provides habitat and food for a variety of animals, including squirrels, birds, deer and insects. In parts of the state, it is one of the only species of tree that exists. Valley oaks provide benefits to humans, too: filtering water and providing shady places to escape the heat.

Although it focuses on the oak, the paper has broader implications for conservation science in a changing climate — especially for species that evolve and adapt slowly. That’s what Sork and Wright were thinking when they initiated the project.

At the time, they hoped to find conservation strategies that could eventually be implemented using genetic information alone — without extensive field experiments.

“Not everyone in the world is going to be able to collect 11,000 seeds and plant them in a common garden,” Sork said.

This article originally appeared in the UCLA Newsroom.